Nicotinic acid, instructions for usewhich will be considered in this article, is a vitamin that takes part in oxidative processes taking place in living cells and is a medicinal product. The medicine is presented in the form of a white powder of sour taste and odorless. It is difficult to dissolve in cold water.

It should be said that nicotinic acid (orvitamin PP) is a vitamin, anti-allergic, detoxifying and hypolipidemic agent that promotes the improvement of carbohydrate metabolism, the expansion of blood vessels, including the brain, the transfer of oxygen into tissues. It participates in the processes of metabolism of fats, amino acids, proteins and purines, as well as in the processes of biosynthesis.

Nicotinic acid, the instruction to whichprovides for the use of vitamin up to twenty-five milligrams a day, at high doses (up to four grams per day) reduces the number of lipoproteins, triglycerides and cholesterol in the blood.

This drug is fast enoughabsorbed from the digestive tract, and after forty minutes it turns into nicotinamide. The vitamin in the liver is metabolized, it is synthesized in the intestine, while it is excreted by the kidneys in the form of a metabolite.

The indications for the use of the drug are: vitamin deficiency, parenteral nutrition, malabsorption, abrupt weight loss, impaired absorption of amino acids, gastrointestinal disease, increased body requirement for vitamin PP, fever, hepatitis, infectious diseases that are chronic, as well as malignant tumors, pregnancy, lactation, stress. Also nicotinic acid, the instruction on which application is applied to the drug, is prescribed for circulatory disturbances in the brain, diseases of the vessels of the extremities, including their spasms, diseases of the genitourinary system, polyneuropathy and microangiopathy.

Nicotinic acid contraindications havethe following: hypersensitivity to the drug, gastric ulcer, gastritis, gout, glaucoma, hypotension, children under two years of age. Also, with caution use this medication for diseases of the facial nerves, colitis, enterocolitis, trophic and non-healing long time wounds.

Nicotinic acid side effects have the following: hyperemia of the skin, redness of the skin of the face, drynessmucous membranes of eyes and skin, as well as arrhythmia, dizziness, nausea and vomiting, skin itching, myalgia, hyperglycemia, paresthesia. All these phenomena can occur when taking large doses of the drug. If vitamin PP is used for a long time, liver dystrophy, facial hyperemia, asthenia, dizziness and headaches, an increase in the content of AST, APF and LDH in the blood can occur.

Use the drug after meals in the following dosages: adults - twenty-five milligrams per day, children older than two years - up to twenty milligrams a day.

It should be remembered that nicotinic acid withuse caution in combination with anticoagulants and antihypertensive drugs. In any case, when used with other medicines it is necessary to consult with a specialist.

In addition, when using nicotinic acidit is necessary to have a balanced diet (products containing methionine) and constant control of liver function. For better digestion in the digestive tract, it is recommended to drink the drug with milk.

Thus, nicotinic acid, the instruction towhich has been described above, is an indispensable medicinal product in the prevention and treatment of many diseases. It takes part in the metabolic and oxidative processes that take place in the body, as well as in the metabolism process.

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