The drug "Gistan" is considered by many consumerseffective enough external means for elimination of allergic rashes on the skin. The medicine is also used for insect bites. Ointment "Gistan" has a pleasant smell. The drug is quickly absorbed, forming a thin film on the skin that transmits oxygen, but protects against allergens and moisture.

Medication "Gistan" instruction refers to the groupglucocorticosteroids for topical application. The active component is mometasone furoate. The active substance, being a synthetic glucocorticosteroid, has an antiexudative, antipruritic and anti-inflammatory effect. Mometasone furoate induces (enhances) the isolation of proteins that suppress the A2 phospholipase and lipocortins, which in turn control the biosynthesis of inflammatory mediators (leukotrienes and prostaglandins).

The drug "Gistan" preventsthe accumulation of neutroviles, which reduces the production of cytokines and inflammatory exudates, delays the migration of macrophages. The drug, due to lowering the formation of the chemotaxis substance, reduces inflammation, stops the development of the primary allergic reaction.

Means of "Gystan". Instructions. Indications.

The drug is prescribed for dermatoses,accompanied by itching and inflammation of the skin (including, with psoriasis, seborrhoea and atopic dermatitis), the treatment of which requires the use of glucocorticosteroids.

Medicinal product "Gystan". Instructions. Contraindications.

No medication is prescribed forhypersensitivity to glucocorticosteroids, components of the drug, with perioral dermatitis, tuberculosis, rosacea, fungal, viral or bacterial infections of the skin, syphilis. The drug "Gystan" does not recommend the use of the instructions for post-vaccination reactions, patients up to two years. No medication is prescribed for lactation. The drug "Gistan" during pregnancy is also not recommended (with prolonged use, application to large areas of damage).

The drug is applied externally, a thin layer ofproblem areas once a day. Duration of the drug from seven to twenty-eight days. More precise terms of use are determined in accordance with the manifested therapeutic effectiveness, tolerability, occurrence and severity of side effects.

With the daily use of the drug "Gistan" for children older than two years with atopic dermatitis, the result of treatment is noted in three weeks.

After the application of the ointment, the development of localreactions. In particular, they include chalk, striae, secondary infection, skin maceration, contact allergic dermatitis, perioral dermatitis, hypopigmentation, hypertrichosis, skin atrophy, acne, folliculitis, paresthesia, itching, burning. When using occlusive dressings, the frequency and severity of adverse events increases.

Overdose is manifested by oppressionfunctioning of the hypothalamic-pituitary-adrenal system (secondary adrenal insufficiency, including). Treatment is carried out according to the symptoms. If necessary, the correction of electrolyte imbalance is prescribed, the drug cancellation (with prolonged use - the gradual cessation of the use of the "Gystan" ointment).

In the absence of results from treatment for two weeks, it is necessary to clarify the diagnosis.

There is the possibility of developing systemic exposure to prolonged application or application on large areas of the skin, especially when using occlusive dressings.

Local irritation in the area of ​​application can cause propylene glycol, which is part of the "Gystan" ointment.

Before use, you need to carefully study the annotation.

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