Hemorrhagic vasculitis (Shenlaine-Henoch disease) belongs to the acquired diathesis, caused by a predominant increase in the permeability of the walls of the vessels.
Shenlaine Genocha disease: pathogenesis
It is based on allergic inflammationsmall capillaries and vessels. As a result, the plasma swims, and the red blood cells exit into the surrounding tissues. The pathohistological picture of the lesion is almost the same as in the nodular periarteritis. But those vessels that are damaged in hemorrhagic vasculitis, even smaller.
Shenlaine Genocha disease: symptoms
It affects mostly young people. The leading symptom is a rash on the lower extremities, having exudative-hemorrhagic character.
They are distinguished by four: rheumatoid, lightning, simple and abdominal purpura. Each of them has its own specific symptoms. A simple purpura, for example, is accompanied by hemorrhagic eruptions on mucous membranes and skin. There is a malaise as a whole, the temperature rises. In rheumatoid purpura, changes occur within the joints (often knee joints). They become extremely painful, swollen. Relatively often in adolescence and childhood there is abdominal purpura. It causes intestinal and gastric bleeding. Severe pain in the abdomen is accompanied by attacks. In vomit masses there is an admixture of blood, stool-like stool. All these phenomena are accompanied by a rise in body temperature. At the same time there are also characteristic eruptions. Less often they precede the abdominal syndrome or arise after. Lightning purple has the same symptoms, but it is so severe that it can lead to death in the first days.
Shenlaine-Genocha disease: recognition
It is important to differentiate it from hemophilia andthrombocytopenic purpura. Recognition is based on the presence of specific and well-recognized exudative hemorrhagic eruptions, joint pains and malaise as a whole. When examining the results of tests, one should take into account the number of platelets - they remain normal, and the parameters of blood coagulation, compression of the blood clot should not be changed.</ p>