Hemorrhagic vasculitis (Shenlaine-Henoch disease) belongs to the acquired diathesis, caused by a predominant increase in the permeability of the walls of the vessels.

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There are several forms of its manifestation. The name "Shenlaine-Genocha" is on the move abroad. The term "hemorrhagic vasculitis" has been used only in Russian medicine since 1959.

Shenlaine Genocha disease: pathogenesis

It is based on allergic inflammationsmall capillaries and vessels. As a result, the plasma swims, and the red blood cells exit into the surrounding tissues. The pathohistological picture of the lesion is almost the same as in the nodular periarteritis. But those vessels that are damaged in hemorrhagic vasculitis, even smaller.

Shenlaine Genocha disease: symptoms

It affects mostly young people. The leading symptom is a rash on the lower extremities, having exudative-hemorrhagic character.

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Nodules can be of different sizes, but mostlysmall, symmetrically located. Eruptions are often accompanied by pain in the joints, itching, fever and malaise as a whole. If the disease proceeds very hard, then they spread and merge into large hemorrhagic spots. Perhaps the emergence of extensive hemorrhages with dying sites. Days through 10-15 the rash, as a rule, disappears, but not for ever. Often it appears again. Because of periarticular edema, changes occur in the joints. Sometimes Shenlaine-Henoch's disease is complicated by hemorrhage into tissues and internal organs. If it occurs in the course of the stomach and intestine, then in the abdomen there are sharp pains. Hemorrhage in the brain is accompanied by the development of paralysis and paresis. Sometimes the changes characteristic of hemorrhagic vasculitis occur not only in the internal organs, but also affect the vessels of the retina of the eyes and the central nervous system.

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Shenlaine Genocha disease: forms

They are distinguished by four: rheumatoid, lightning, simple and abdominal purpura. Each of them has its own specific symptoms. A simple purpura, for example, is accompanied by hemorrhagic eruptions on mucous membranes and skin. There is a malaise as a whole, the temperature rises. In rheumatoid purpura, changes occur within the joints (often knee joints). They become extremely painful, swollen. Relatively often in adolescence and childhood there is abdominal purpura. It causes intestinal and gastric bleeding. Severe pain in the abdomen is accompanied by attacks. In vomit masses there is an admixture of blood, stool-like stool. All these phenomena are accompanied by a rise in body temperature. At the same time there are also characteristic eruptions. Less often they precede the abdominal syndrome or arise after. Lightning purple has the same symptoms, but it is so severe that it can lead to death in the first days.

Shenlaine-Genocha disease: recognition

It is important to differentiate it from hemophilia andthrombocytopenic purpura. Recognition is based on the presence of specific and well-recognized exudative hemorrhagic eruptions, joint pains and malaise as a whole. When examining the results of tests, one should take into account the number of platelets - they remain normal, and the parameters of blood coagulation, compression of the blood clot should not be changed.

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