Surely many have heard of such a disease as vasculitis. What is it, do not everyone know, so we offer a brief information about one common form - hemorrhagic.
The reasons for the appearance of vasculitis to the end are notbut their development is associated with an abnormal reaction of the immune system, with transferred or present infections, with the taking of certain medications. Clear classification does not exist due to the difficulties in differentiating vasculitis. All forms of the disease occur with skin lesions, 80% are characterized by joint syndrome. The process can develop in large and small vessels of any organs.
One of the most frequently encountered species is thea typical representative of systemic autoimmune vasculitis is hemorrhagic, which is also called Shenlen-Henoch disease, anaphylactoid purpura, or capillarotoxicosis.
Hemorrhagic vasculitis - what is it?
The disease is more common in children,mainly in boys. With hemorrhagic vasculitis, there is a lesion of the skin, joints, kidneys, digestive organs, rarely light. Only small vessels are involved in the process: capillaries and arterioles.
Disease, as a rule, has a sharp beginning. Usually this happens 2-3 weeks after the acute respiratory infection. The first sign is skin rashes - purpura. Then articular pain and abdominal (related to the stomach) syndrome occur, later the kidney joins. In most cases, there is a fever, weakness, poor appetite, weight loss. The disease can occur in a chronic form with recurrent relapses.
Purple is a typical manifestation of this form,as a cutaneous hemorrhagic vasculitis. It is present in all patients. Eruptions have the appearance of sharply outlined papules ranging in size from 1 to 5 mm, which subsequently merge. Elements usually protrude above the skin surface and do not disappear when pressed. The rash is located symmetrically and is localized, as a rule, on the extensor of the extremities, around large joints, on the buttocks and legs. Less often it can be found on the face, back, stomach and chest. After a few days, the rashes turn pale and acquire a brown shade, forming a pigmentation. At the same time next to the old spots appear fresh, making the skin look mottled. The rash is abundant or meager, it can last for years.
The second most common is the articulara syndrome that accompanies hemorrhagic vasculitis. What it is? Pain in large joints: ankle and knee. Despite enough severe pain, arthritis with vasculitis is reversible, there is almost no deformation in the joints.
In 50% of patients, mainly in children, developsabdominal syndrome, which is expressed in paroxysmal, sudden pain in the abdomen, more often in the navel. In addition, bloating, vomiting and diarrhea with an admixture of blood are observed. There are cases of surgical complications: intestinal obstruction, intestinal perforation, peritonitis.
Kidney signs accompanying vasculitis - thatis this? The nephrotic syndrome manifests itself in the form of glomerulonephritis and occurs in 30-60% of patients. It often occurs in the first year of the disease, sometimes after the disappearance of extrarenal manifestations or with another relapse. The main symptom of glomerulonephritis is the presence of blood in the urine.
Hemorrhagic vasculitis in children may occurin severe form in the form of fulminant purpura, in which multiple hemorrhages under the skin, accompanied by fever and arterial hypotension, appear for several hours.</ p>